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In Collaboration with Research Corporation Technologies (RCT)case_study_abdurintm_the_smallest_and_best-in-class_ab-like_scaffold_1

 

  • Derived from human or primate IgG1
  • Non immunogenic
  • Small size (12-15kDa), enable better tissue penetration
  • Retains hFcRn binding and extended serum: half-life 8-16 hours in primates and mice
  • Multimeric and multifunctional molecules can be constructed
  • Readily produced in E. coli, Pichia and CHO cells
  • Ideally suited for payload delivery or as a fusion to other proteins
  • Strong IP position by RCT

case_study_abdurintm_the_smallest_and_best-in-class_ab-like_scaffold_2