Job opportunities

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ADMINISTRATION DEPT.

HR Assistant - Ref. 115A

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Job Description

We are currently recruiting a junior Hr Assistant.

The HR Assistant’s primary responsibility is to support the HR Team MANAGER in the daily activities and generally assisting the HR Advisers.

The successful candidate will be a strong HR administrator having the responsibility to answer to all document inbound phone calls/e-mails and to provide Human Resources and information to employees.

The role holder will be required to interpret HR policies and procedures to solve and answer employee's queries. 

Role Responsibility 

• Provide administrative support and produce letters as required to the HR Manager
• Tracking employee absences
• Arranging job interviews
• Preliminary activities of payment salaries / wages trough home banking
• Managing employment contracts and consultancy agreements
• Maintaining personnel files for the office to ensure confidentiality and compliance with all legal regulations
• Preparing files to report for Italian and European grants

 Minimum Requirements 

• Ability to handle confidential and sensitive information with the appropriate discretion
• Organizational skills needed to successfully manage time scheduling, prioritize effectively and handle multiple deadlines
• Previous Administration experience, ideally within an HR function
• Advanced knowledge of Word, PowerPoint etc
• Strong Excel skills including ability to produce detailed analysis and reports with 100% accuracy.
• Excellent working knowledge of employment law and practices.
• High level of spoken and written English

Qualified Accountant  - Ref. 111A

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Job description

We are seeking a qualified accountant for our finance department to assist our team with costs analysis and invoicing.  The successful candidate will be qualified with a Bachelor’s degree and will ideally have several years of work-experience. Reporting directly to the managing director, the candidate will be responsible for:

• VAT registration procedures
• Bank reconciliations
• Preparation of Cash Flows e Cash Forecasts
• Preparation of the annual balance sheet
• Organizing F24 and other fiscal payments

Minimum Requirements

A sound knowledge of standard financial and administrative procedures is required, and the ability to work as part of a group is essential.  Proficiency with standard computer software packages such as  MS Word & Excel and financial software packages is required, as is a good level of written and spoken English.

Administrative Secretary - Ref. 109A

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We are looking for a motivated and flexible secretary. The candidate should be young, bilingual (English and Italian mother tongue) with a minimum of two years' relevant experience in the same role.

 Job description

• devising and maintaining office systems, including data management and filing;
• organizing meetings;
• arranging travel, visas and accommodation;
• filtering phone calls, enquiries and requests, and handling them when appropriate;
• translating full documents, emails and promotional material to and from English;
• dealing with incoming email, faxes and regular mail;
• taking dictation.

Minimum Requirements

In addition to relevant experience and secretarial knowledge, candidates will need to show evidence of the  following:

• exceptional written and oral communication skills;
• excellent word processing and good IT skills, including knowledge of a range of software packages;
• ability to work under pressure and to tight deadlines;
• good organizational and time management skills;
• ability to research, digest, analyse and present material clearly;
• flexibility and adaptability to juggle a range of different tasks and to work extra hours when necessary to meet deadlines;
• discretion and an understanding of confidentiality issues.

SCIENTIFIC DEPT.

Cellular Neurobiology Scientist - Lab Head - Ref. 114A

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Job Description

We are looking for a motivated, flexible and experienced Scientist with a strong background in the cell biology of neurodegenerative disorders. The candidate should have several years of experience in research with primary neuronal cultures and neuronal differentiation from mouse and/or human ES/iPS cells. In addition, experience with their use in microtiter-based formats is a plus. Experience in organotypic slice cultures from the CNS is of advantage. The candidate is expected to participate in and lead drug discovery projects.
The work will be performed at IRBM-PROMIDIS in the IRBM Science Park in Pomezia, Rome, where the successful applicant will be a member of a multidisciplinary international team investigating the biology of Huntington’s Disease.
If you are interested in the biotech industry and are a highly motivated individual that would like to actively contribute to the investigations of a neurodegenerative disorder for which currently no cure exists, we are looking forward to your application.

Minimum Requirements

• PhD degree in biology, biochemistry or an equivalent Life Science and minimum of two years postdoctoral experience
• Strong publication record
• Experience in training and mentoring laboratory personnel
• Excellent communication skills in English and team working capabilities

 Biology Scientist – Phage Display Expert - Ref. 113A

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Job description

We are looking for a motivated, flexible and experienced Scientist with a strong background in the Phage Display technologies and protein biochemistry. The candidate should have experience in construction and selection of peptides/antibodies Phage Display Libraries on M13/Lambda, in developing microtiter plate readouts such as ELISA and other immunoassay technologies. Experience in protein expression/purification, biochemical characterization and enzymatic assays is an advantage. The candidate is expected to participate in and lead Phage Display projects, to write reports, make presentations, and communicate with other IRBM or external scientists.

 Minimum Requirements

• PhD degree in biology, biochemistry or an equivalent Life Science and minimum of two years postdoctoral experience
• Capabilities to plan and execute independent research while having a strong propensity to team working
• Excellent communication skills in English

PK/PD and PBPK position – Ref. 112A

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Quantitative PK/PD Relationships: Pharmacokinetic/pharmacodynamic modelling is a critical activities related with the modern interpretation and prediction of pharmacological and toxicological hypothesis. Quantitative, mathematical links between drug concentration and drug effect, both in vitro and in vivo allow a rational testing of phar¬macological and toxicological hypotheses but also a more clear interpretation of mechanisms of action. In the phase of design a new therapeutic approach the selection of the appropriate biomarker is invaluable, and generate a PK/PD model is very important in designing clinical PoC scenarios, and may also be used in the regulatory setting.

Physiologically Based Pharmacokinetics: recently developed physiologically based pharmacokinetics (PBPK) methods are an extension of existing in silico tools, that allow early simulation of in vivo pharmacokinetics behavior based on traditional general physiology and a small set of experimentally determined (in vitro) or simulated parameters. PBPK is a very important tool to identify predictors for PK behavior based on molecular structure, but can also be used to probe in vivo mechanism of action and toxicity issues. The precision of predictions of human pharmacokinetics increases when allometry, complex Dedrick approaches and PBPK are applied.

Job description:

•  Support the project team with the PBPK prediction to generate predictor of the PK behavior of the new agents
• Advance the understanding of the action and in vivo behavior novel drug candidates through the design, analysis, and interpretation of preclinical and clinical pharmacokinetic (PK) and pharmacokinetic/pharmacodynamic (PK/PD) studies.
• Aid in the development of novel drug candidates by preparing PK, PK/PD, and/or modeling and simulation components of study protocols, reports, project summaries, development plans, and regulatory submissions.

Minimum Requirements:

• Advanced degree (Ph.D., Pharm. D., and/or M.D.) in Biomedical, Biological or Pharmaceutical Science with industry experience.
• In depth knowledge of PK and PK/PD concepts with a strong clinical pharmacology background.
• Proficiency in PK and PK/PD analysis utilizing standard modeling software (NONMEM, ADAPT-II, R/S-Plus, WinNonlin, etc.) and their application to the drug development is a pre-requisite.
• Experience designing, conducting and interpreting studies in population PK, PK/PD correlations, modeling and simulation
• Excellent oral and written communication skills and a proven track record of working effectively in a dynamic, collaborative, team-oriented setting.  

 Collaborate with drug development teams by serving as a key contact for PK and PK/PD related issues and providing the PK and PK/PD perspective of drug candidates.

Biochemistry Scientist - Ref. 108A

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Job Description

We are looking for a motivated, flexible and experienced Scientist with a strong background in immunoassay technologies and protein biochemistry. The candidate should have several years of experience in developing microtiter plate readouts such as ELISA, TR-FRET or alpha-screen assays. Experience in utilizing immunoassay readouts for biomarker discovery in clinical samples is a plus. In addition, knowledge in protein purification and labeling methods is of advantage. The candidate is expected to participate in and lead drug discovery projects.

The work will be performed at IRBM-PROMIDIS in the IRBM Science Park in Pomezia, Rome, where the successful applicant will be a member of a multidisciplinary international team investigating the biology of Huntington’s Disease.

If you are interested in the biotech industry and are a highly motivated individual that would like to actively contribute to the investigations of a neurodegenerative disorder for which currently no cure exists, we are looking forward for your application.

Minimum Requirements

• PhD degree in biology, biochemistry or an equivalent Life Science and minimum of two years postdoctoral experience
• Strong publication record
• Experience in training and mentoring laboratory personnel
• Excellent communication skills in English and team working capabilities

Biochemistry Technician - Ref. 107A

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Job Description

We are looking for a motivated and flexible team player with theoretical and practical background in immunoassay technologies including ELISA, HTRF or Western blotting. In addition, experience with protein purification methods from bacterial and mammalian expression systems, protein biochemistry and standard molecular and cell biology techniques is an advantage. The applicant is expected to plan, conduct, and discuss scientific experiments in a team environment.

The work will be performed at IRBM-PROMIDIS in the IRBM Science Park in Pomezia, Rome, where the successful applicant will be a member of a multidisciplinary international team investigating the biology of Huntington’s Disease.

If you are interested in obtaining work experience in the biotech industry and are a highly motivated individual that would like to actively contribute to the investigations of a neurodegenerative disorder for which currently no cure exists, we are looking forward for your application.

Minimum Requirements

• Master’s or Diploma degree in biology, biochemistry or an equivalent
• Interest in and flexibility to learn new experimental techniques
• Good communication skills in English and team working capabilities

Molecular and Cell Biology Scientist - Ref. 106A

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Job Description

We are looking for a motivated, flexible and experienced Scientist with a strong background in molecular biology and cell biology. The candidate should have several years of experience in studying molecular pathways and gene function via genetic and pharmacological approaches. In addition, experience in analysis of gene expression at the RNA and protein level, expression vector cloning, site-directed mutagenesis and knowledge in neurobiology is an advantage. The candidate is expected to participate in and lead drug discovery projects.

The work will be performed at IRBM-PROMIDIS in the IRBM Science Park in Pomezia, Rome, where the successful applicant will be a member of a multidisciplinary international team investigating the biology of Huntington’s Disease.

If you are interested in the biotech industry and are a highly motivated individual that would like to actively contribute to the investigations of a neurodegenerative disorder for which currently no cure exists, we are looking forward for your application.

Minimum Requirements

• PhD degree in biology, biochemistry or an equivalent Life Science and minimum of two years postdoctoral experience
• Strong publication record
• Experience in training and mentoring laboratory personnel
• Excellent communication skills in English and team working capabilities

Molecular and Cell Biology Technician - Ref. 105A

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Job Description

We are looking for a motivated and flexible team player with theoretical and practical background in standard molecular biology and cell biology laboratory techniques including expression vector cloning, site-directed mutagenesis, analysis of gene expression at the RNA and protein level, and functional studies in cell culture using genetic and pharmacological approaches. In addition, experience with protein detection methods based on immunoassay technologies is an advantage. The applicant is expected to plan, conduct, and discuss scientific experiments in a team environment.

The work will be performed at IRBM-PROMIDIS in the IRBM Science Park in Pomezia, Rome, where the successful applicant will be a member of a multidisciplinary international team investigating the biology of Huntington’s Disease.

If you are interested in obtaining work experience in the biotech industry and are a highly motivated individual that would like to actively contribute to the investigations of a neurodegenerative disorder for which currently no cure exists, we are looking forward for your application.

Minimum Requirements

• Master’s or Diploma degree in biology, biochemistry or an equivalent
• Interest in and flexibility to learn new experimental techniques
• Good communication skills in English and team working capabilities

Cellular Neurobiology Scientist - Ref. 104A

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Job Description

We are looking for a motivated, flexible and experienced Scientist with a strong background in the cell biology of neurodegenerative disorders. The candidate should have several years of experience in research with primary neuronal cultures and neuronal differentiation from mouse and/or human embryonic stem cells. In addition, experience with the preparation and use of organotypic cultures from the CNS is an advantage. The candidate is expected to participate in and lead drug discovery projects.

The work will be performed at IRBM-PROMIDIS in the IRBM Science Park in Pomezia, Rome, where the successful applicant will be a member of a multidisciplinary international team investigating the biology of Huntington’s Disease.

If you are interested in the biotech industry and are a highly motivated individual that would like to actively contribute to the investigations of a neurodegenerative disorder for which currently no cure exists, we are looking forward for your application.

Minimum Requirements

• PhD degree in biology, biochemistry or an equivalent Life Science and minimum of two years postdoctoral experience
• Strong publication record
• Experience in training and mentoring laboratory personnel
• Excellent communication skills in English and team working capabilities

Cellular Neurobiology Technician - Ref. 103A

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Job description

We are looking for a motivated and flexible team player with theoretical and practical background in cellular neurobiological laboratory techniques including the preparation and culture of primary neurons, stem cell-derived neurons, and the use of standard neuronal cell lines. Experience with functional studies in these models using genetic and pharmacological approaches is a must. In addition, experience with the preparation and use of organotypic cultures from the CNS is an advantage.

The work will be performed at IRBM-PROMIDIS in the IRBM Science Park in Pomezia, Rome, where the successful applicant will be a member of a multidisciplinary international team investigating the biology of Huntington’s Disease. The applicant is expected to plan, conduct, and discuss scientific experiments in a team environment.

If you are interested in obtaining work experience in the biotech industry and are a highly motivated individual that would like to actively contribute to the investigations of a neurodegenerative disorder for which currently no cure exists, we are looking forward for your application.

Minimum Requirements

• Master’s or Diploma degree in biology, biochemistry or an equivalent
• Interest in and flexibility to learn new experimental techniques
• Good communication skills in English and team working capabilities

Biology - Ref. 102A - Expert in assay development and optimization for high throughput screening.

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Minimum Requirements:

• Degree in one of the following disciplines: Biology, Biotechnology, Pharmaceutical Technologies, Biomedical Engineering
• Ph.D. or equivalent experience in a pharmaceutical research lab
• Strong propensity for the technological and IT aspects related to the biotechnological and pharmaceutical research.
• In particular, the candidates should have at least one of the following :

Basic knowledge of computer networks and programming languages Basic knowledge of laboratory automation

• Ability to operate in a context of biological / pharmaceutical research
• Propensity to work planning

Chemistry - Ref. 101A - DMPK Scientist.

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Design, conduct and analyze in vivo and/or in vitro DMPK studies to support drug discovery and preclinical development. Obtain/interpret bioanalytical/pharmacokinetic and/ or in vitro findings, write reports, make presentations, and communicate with other DMPK and Med Chem scientists. Requires PhD or MS and 2+ years industry experience with in vivo and/or in vitro DMPK; knowledge of enzyme kinetics and hands-on DMPK skills including bioanalytical method development using LC/MS/MS; drug quantitation in various matrices such as plasma and tissues; sample preparation using liquid handling robots, and computational PK analysis using Watson or similar software. Previous experience in the design of in vivo experiments or metabolite identification is a plus.

Minimum Requirements:

The candidate must have: Hands-on experience on mass spectrometry and HPLC as applied to in vitro & in vivo drug metabolism. Working knowledge of other instrumentation including UPLC, radiometric, LSC, fluorescence detectors is a plus.

Innovative, independent and goal-oriented; able to plan and execute own research while being a good team player. Able to work in interdisciplinary and multicultural teams where English is the common language.

 
SITE SERVICE DEPT.

Warehouse Assistant - Ref. 110A

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Job description

We are looking for a young warehouse assistant  who will record stock correctly to ensure the accuracy of our stock control system.
In particular the ideal candidate will manage:
Msds related to biological and chemical compounds
Lgs 17/2010 related to spare parts of machinery and site services

The main duties of the role are: 

• Supporting invetory activities identifying issues resolving stock problems to make sure that stock levels are controlled to maximize availability
• Delivering goods to applicants
• Reception of incoming material shipments
• Access and utilize appropriate internal systems
• Verify quantity of stock and chemical compounds