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structural_biology_and_metabolomics

Nuclear magnetic resonance (NMR) spectroscopy is a powerful tool in the studies of structural biology, metabolomics, clinical research solutions, functional genomics, structure/activity relationship, drug discovery, macromolecule and small molecule analysis.

We use a number of methods, including relaxation measurements, chemical shift mapping, transfer NOE, Saturation Transfer Difference(STD), dynamics and 2D or 3D triple resonance NMR experiments.

The current instrumentation of our laboratory includes two high field Bruker 600MHz, and a 500 MHz NMR spectrometers, which is capable of various multi-dimensional 1H / 2H / 13C / 15N/ 31P/ 19F NMR experiments.